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1

Prostromelysin-1 (proMMP-3) stimulates plasminogen activation by tissue-type plasminogen activator

Begoña Arza, Marc F. Hoylaerts, Jordi Félez, Désiré Collen, H. Roger Lijnen

Journal:

Year:

2000

Language:

english

File:

PDF, 525 KB

english, 2000

2

Critical role of glutamic acid 202 in the enzymatic activity of stromelysin-1 (MMP-3)

Begoña Arza, Marc De Maeyer, Jordi Félez, Désiré Collen, H. Roger Lijnen

Journal:

Year:

2001

Language:

english

File:

PDF, 441 KB

english, 2001

3

Review of the major hypertension trials in the elderly

Jan Staessen, Robert Fagard, Paul Lijnen, Roger Van Hoof, Antoon Amery

Journal:

Cardiovascular Drugs and Therapy

Year:

1991

Language:

english

File:

PDF, 1.10 MB

english, 1991

4

Deleterious effects of lack of cardiac PAI-1 after coronary occlusion in mice and their pathophysiologic determinants

A. K. M. Tarikuz Zaman, Satoshi Fujii, David J. Schneider, Douglas J. Taatjes, H. Roger Lijnen, Burton E. Sobel

Journal:

Histochemistry and Cell Biology

Year:

2007

Language:

english

File:

PDF, 713 KB

english, 2007

5

Thrombolytic efficacy of recombinant human microplasmin in a canine model of copper coil-induced coronary artery thrombosis

Christophe Dommke, Oliver Turschner, Jean-Marie Stassen, Frans Van de Werf, H. Roger Lijnen, Peter Verhamme

Journal:

Journal of Thrombosis and Thrombolysis

Year:

2010

Language:

english

File:

PDF, 525 KB

english, 2010

6

Functional interactions between pancreatic beta cells and (pre)adipocytes

Valerie Christiaens, Rebecca Sujatha, Karine H. Hellemans, Daniel Pipeleers, H. Roger Lijnen

Journal:

Endocrine (Springer)

Year:

2010

Language:

english

File:

PDF, 445 KB

english, 2010

7

Effect of weight loss on gelatinase levels in obese mice

Matthias Van Hul, Henri Roger Lijnen

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2011

Language:

english

File:

PDF, 513 KB

english, 2011

8

Functional hierarchy of plasminogen kringles 1 and 4 in fibrinolysis and plasmin-induced cell detachment and apoptosis

Benoît Ho-Tin-Noé, Gertrudis Rojas, Roger Vranckx, H. Roger Lijnen, Eduardo Anglés-Cano

Journal:

Year:

2005

Language:

english

File:

PDF, 456 KB

english, 2005

9

Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation

Carmeliet, Peter, Moons, Lieve, Lijnen, Roger, Baes, Myriam, Lemaître, Vincent, Tipping, Peter, Drew, Angela, Eeckhout, Yves, Shapiro, Steve, Lupu, Florea

Journal:

Nature Genetics

Year:

1997

File:

PDF, 997 KB

1997

10

Host-derived plasminogen activator inhibitor-1 (PAI-1) concentration is critical for in vivo tumoral angiogenesis and growth

Bajou, Khalid, Maillard, Catherine, Jost, Maud, Lijnen, Roger H, Gils, Ann, Declerck, Paul, Carmeliet, Peter, Foidart, Jean-Michel, Noel, Agnès

Journal:

Year:

2004

Language:

english

File:

PDF, 194 KB

english, 2004

11

Effect of endurance training on blood pressure at rest, during exercise and during 24 hours in sedentary men

Roger Van Hoof, Peter Hespel, Robert Fagard, Paul Lijnen, Jan Staessen, Antoon Amery

Journal:

The American Journal of Cardiology

Year:

1989

Language:

english

File:

PDF, 556 KB

english, 1989

12

Urapidil-induced hemodynamic changes in humans

Edith Bielen, Robert Fagard, Jan Staessen, Paul Lijnen, Roger Van Hoof, Antoon Amery

Journal:

The American Journal of Cardiology

Year:

1989

Language:

english

File:

PDF, 737 KB

english, 1989

13

Mean and range of the ambulatory pressure in normotensive subjects from a meta-analysis of 23 studies

Jan A. Staessen, Robert H. Fagard, Paul J. Lijnen, Lutgarde Thijs, Roger Van Hoof, Antoon K. Amery

Journal:

The American Journal of Cardiology

Year:

1991

Language:

english

File:

PDF, 975 KB

english, 1991

14

On the future of thrombolytic therapy for acute myocardial infarction

Désiré Collen, Henri Roger Lijnen

Journal:

The American Journal of Cardiology

Year:

1993

Language:

english

File:

PDF, 649 KB

english, 1993

15

On the molecular interactions between plasminogen-staphylokinase, α2-antiplasmin-formula> and fibrin

H. Roger Lijnen, Berthe Van Hoef, Osamu Matsuo, Désiré Collen

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1992

Language:

english

File:

PDF, 434 KB

english, 1992

16

Neutralization of α2-antiplasmin by microplasmin: A randomized, double-blind, placebo-controlled, ascending-dose study in healthy male volunteers

Steve Pakola, Geraldine Cahillane, Jean-Marie Stassen, H. Roger Lijnen, Peter Verhamme

Journal:

Clinical Therapeutics

Year:

2009

Language:

english

File:

PDF, 183 KB

english, 2009

17

Effect of premature aging on murine adipose tissue

Bianca Hemmeryckx, Marc F. Hoylaerts, H. Roger Lijnen

Journal:

Experimental Gerontology

Year:

2012

Language:

english

File:

PDF, 761 KB

english, 2012

18

Corrigendum to “Effect of premature ageing on murine adipose tissue” [Experimental Gerontology (2012) 256–262]

Hemmeryckx, Bianca, Hoylaerts, Marc F., Lijnen, H. Roger

Journal:

Experimental Gerontology

Year:

2012

Language:

english

File:

PDF, 111 KB

english, 2012

19

Differential expression of plasminogen activator inhibitor-1, tumor necrosis factor-α, TNF-α converting enzyme and ADAMTS family members in murine fat territories

Gabor Voros, Erik Maquoi, Désiré Collen, H.Roger Lijnen

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2003

Language:

english

File:

PDF, 209 KB

english, 2003

20

Inactivation of the serpin α2-antiplasmin by stromelysin-1

H.Roger Lijnen, Berthe Van Hoef, Désiré Collen

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

2001

Language:

english

File:

PDF, 353 KB

english, 2001

21

1 Mechanisms of physiological fibrinolysis

H. Roger Lijnen, Desire Collen

Journal:

Baillière's Clinical Haematology

Year:

1995

Language:

english

File:

PDF, 1.21 MB

english, 1995

22

10 New thrombolytic agents and strategies

Desire Collen, H. Roger Lijnen

Journal:

Baillière's Clinical Haematology

Year:

1995

Language:

english

File:

PDF, 920 KB

english, 1995

23

On the Rolw of the Carbohydrate Side Chains of Human Plasminogen in Its Interaction with α2-Antiplasmin and Fibrin

H. Roger LIJNEN, Berthe VAN HOEF, Désiré COLLEN

Journal:

Year:

1981

Language:

english

File:

PDF, 666 KB

english, 1981

24

Influence of cyanogen-bromide-digested fibrinogen on the kinetics of plasminogen activation by urokinase

H. Roger LIJNEN, Berthe VAN HOEF, Désiré COLLEN

Journal:

Year:

1984

Language:

english

File:

PDF, 438 KB

english, 1984

25

Characterization of the high-affinity interaction between human plasminogen and pro-urokinase

H. Roger LIJNEN, Concepcion ZAMARRON, Désiré COLLEN

Journal:

Year:

1985

Language:

english

File:

PDF, 380 KB

english, 1985

26

A monoclonal antibody directed against the high-affinity lysine-binding site (LBS) of human plasminogen : Role of LBS in the regulation of fibrinolysis

Paul HOLVOET, Henri Roger LIJNEN, Désiré COLLEN

Journal:

Year:

1986

Language:

english

File:

PDF, 560 KB

english, 1986

27

Characterization of functional domains in human tissue-type plasminogen activator with the use of monoclonal antibodies

Paul HOLVOET, Henri Roger LIJNEN, Désiré COLLEN

Journal:

Year:

1986

Language:

english

File:

PDF, 668 KB

english, 1986

28

Differential reactivity of Glu-Gly-Arg-CH2Cl, a synthetic urokinase inhibitor, with single-chain and two-chain forms of urokinase-type plasminogen activator

H. Roger LIJNEN, Berthe VAN HOEF, Désiré COLLEN

Journal:

Year:

1987

Language:

english

File:

PDF, 540 KB

english, 1987

29

Amino-acid sequence of human α2-antiplasmin

H. Roger LIJNEN, William E. HOLMES, Berthe VAN HOEF, Björn WIMAN, Henri RODRIGUEZ, Désiré COLLEN

Journal:

Year:

1987

Language:

english

File:

PDF, 969 KB

english, 1987

30

Activation with plasmin of two-chain urokinase-type plasminogen activator derived from single-chain urokinase-type plasminogen activator by treatment with thrombin

H. Roger LIJNEN, Berthe VAN HOEF, Désiré COLLEN

Journal:

Year:

1987

Language:

english

File:

PDF, 614 KB

english, 1987

31

Enzymatic properties of single-chain and two-chain forms of a Lys158→ Glu158 mutant of urokinase–type plasminogen activator

H. Roger LIJNEN, Berthe VAN HOEF, Luc NELLES, William E. HOLMES, Désiré COLLEN

Journal:

Year:

1988

Language:

english

File:

PDF, 343 KB

english, 1988

32

Structural and functional characterization of mutants of recombinant single-chain urokinase-type plasminogen activator obtained by site-specific mutagenesis of Lys158, Ile159 and Ile160

H. Roger LIJNEN, Luc NELLES, Berthe VAN HOEF, Eddy DEMARSIN, Désiré COLLEN

Journal:

Year:

1988

Language:

english

File:

PDF, 962 KB

english, 1988

33

Biochemical properties of conjugates of urokinase-type plasminogen activator with a monoclonal antibody specific for cross-linked fibrin

Maria DEWERCHIN, H. Roger LIJNEN, Berthe Van HOEF, Frans De COCK, Désiré COLLEN

Journal:

Year:

1989

Language:

english

File:

PDF, 939 KB

english, 1989

34

Construction and characterization of a recombinant murine monoclonal antibody directed against human fibrin fragment-D dimer

Anne-Mieke VANDAMME, Frank BULENS, Hilde BERNAR, Luc NELLES, Roger H. LIJNEN, Désiré COLLEN

Journal:

Year:

1990

Language:

english

File:

PDF, 1.07 MB

english, 1990

35

Construction and characterization of a functional chimeric murine – human antibody directed against human fibrin fragment-D dimer

Frank BULENS, Anne-Mieke VANDAMME, Hilde BERNAR, Luc NELLES, Roger H. LIJNEN, Désiré COLLEN

Journal:

Year:

1991

Language:

english

File:

PDF, 872 KB

english, 1991

36

Characterization of a recombinant chimeric plasminogen activator composed of a fibrin fragment-d-dimer-specific humanized monoclonal antibody and a truncated single-chain urokinase

Anne-Mieke VANDAMME, Maria DEWERCHIN, H. Roger LIJNEN, Hilde BERNAR, Frank BULENS, Luc NELLES, Désiré COLLEN

Journal:

Year:

1992

Language:

english

File:

PDF, 871 KB

english, 1992

37

Biochemical characterization of single-chain chimeric plasminogen activators consisting of a single-chain Fv fragment of a fibrin-specific antibody and single-chain urokinase

Paul HOLVOET, Yves LAROCHE, Henri Roger LIJNEN, Berthe VAN HOEF, Els BROUWERS, Frans DE COCK, Marc LAUWEREYS, Yannick GANSEMANS, Désiré COLLEN

Journal:

Year:

1992

Language:

english

File:

PDF, 896 KB

english, 1992

38

Mechanisms of activation of mammalian plasma fibrinolytic systems with streptokinase and with recombinant staphylokinase

Desiré COLLEN, Berthe VAN HOEF, Bernhard SCHLOTT, Manfred HARTMANN, Karl-Heinz GÜHRS, H. Roger LIJNEN

Journal:

Year:

1993

Language:

english

File:

PDF, 913 KB

english, 1993

39

Molecular assembly of plasminogen and tissue-type plasminogen activator on an evolving fibrin surface

Valérie FLEURY, Stéphane LOYAU, H. Roger LIJNEN, Willem NIEUWENHUIZEN, Eduardo ANGLÉS-CANO

Journal:

Year:

1993

Language:

english

File:

PDF, 871 KB

english, 1993

40

Interaction of staphylokinase with different molecular forms of plasminogen

H. Roger LIJNEN, Berthe VAN HOEF, Désiré COLLEN

Journal:

Year:

1993

Language:

english

File:

PDF, 916 KB

english, 1993

41

Characterization of the Binding of Urokinase-type Plasminogen Activator (u-PA) to Plasminogen, to Plasminogen-activator Inhibitor-1 and to the u-PA Receptor

H. Roger Lijnen, Frans De Cock, Désiré Collen

Journal:

Year:

1994

Language:

english

File:

PDF, 929 KB

english, 1994

42

Characterization of the Murine Plasma Fibrinolytic System

H. Roger Lijnen, Berthe Van Hoef, Veerle Beelen, Désiré Collen

Journal:

Year:

1994

Language:

english

File:

PDF, 1.16 MB

english, 1994

43

Characterization of the Interaction Between Plasminogen and Staphylokinase

H. Roger Lijnen, Frans De Cock, Berthe Van Hoef, Bernhard Schlott, Désiré Collen

Journal:

Year:

1994

Language:

english

File:

PDF, 833 KB

english, 1994

44

Structural Domains of Streptokinase Involved in the Interaction with Plasminogen

Pedro Rodríguez, Pablo Fuentes, Mario Barro, Julio G. Alvarez, Emilio Muñoz, Désiré Collen, H. Roger Lijnen

Journal:

Year:

1995

Language:

english

File:

PDF, 1005 KB

english, 1995

45

Functional Properties of a Recombinant Chimeric Protein with Combined Thrombin Inhibitory and Plasminogen-Activating Potential

H. Roger Lijnen, Stephan Wnendt, Johannes Schneider, Elke Janocha, Berthe Van Hoef, Désiré Collen, Gerd J. Steffens

Journal:

Year:

1995

Language:

english

File:

PDF, 1.02 MB

english, 1995

46

Characterization of the murine plasminogen/urokinase-type plasminogen-activator system

H. Roger Lijnen, Berthe Van Hoef, Désiré Collen

Journal:

Year:

1996

Language:

english

File:

PDF, 1.13 MB

english, 1996

47

Enzymatic Properties of Phage-Displayed Fragments of Human Plasminogen

Ignace Lasters, Nathalie Van Herzeele, H. Roger Lijnen, Désiré Collen, Laurent Jespers

Journal:

Year:

1997

Language:

english

File:

PDF, 805 KB

english, 1997

48

Matrix metalloproteinase inhibition affects adipose tissue mass in obese mice

Matthias Van Hul, Florea Lupu, Tom Dresselaers, Johan Buyse, H Roger Lijnen

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2012

Language:

english

File:

PDF, 556 KB

english, 2012

49

Exfoliative Dermatitis Due to Immunologically Confirmed Carbamazepine Hypersensitivity

Roger J. J. Troost, Arnold P. Oranje, Raf L. P. Lijnen, Robbert Benner, Errol P. Prens

Journal:

Pediatric Dermatology

Year:

1996

Language:

english

File:

PDF, 1.14 MB

english, 1996

50

Guiding a docking mode by phage display: selection of correlated mutations at the staphylokinase-plasmin interface

Laurent Jespers, H.Roger Lijnen, Sophie Vanwetswinkel, Berthe Van Hoef, Katleen Brepoels, Désiré Collen, Marc De Maeyer

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 286 KB

english, 1999

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